14.4 Oligoarticular Juvenile Idiopathic Arthritis (JIA): can extension be predicted?
نویسندگان
چکیده
Background Oligoarticular JIA is presently unpredictable in its course and can become more severe after an initially mild onset. We examined the cellular and molecular composition of the first synovial fluid (SF) aspirates from oligoarticular JIA patients to discover markers that predict an increase in number of joints involved and thus, extension to more severe phenotype (extended oligoarticular JIA).
منابع مشابه
Juvenile Idiopathic Arthritis Onset in a Neonate: A Rare Case Report
Background: A common type of chronic arthritis in children and adolescents is juvenile idiopathic arthritis (JIA).According to the International League of Associations for Rheumatology (ILAR) classification, JIA diagnostic criteria include age under 16 years and disease duration of six-weeks. Based on the number of involved joints in the first sixmonths of disease onset, JIA is categorized into...
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Introduction Predicting disease course in Juvenile Idiopathic Arthritis (JIA) is difficult. During the first 6 months of oligoarticular JIA (O-JIA) disease presents with 4 or fewer affected joints, however after 6 or more months severity might increase with more than 4 joints involved (extended O-JIA), or persist with 4 or fewer joints affected (persistent O-JIA). However patients do not show a...
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Introduction Predicting disease course in Juvenile Idiopathic Arthritis (JIA) is difficult. During the first 6 months of oligoarticular JIA (O-JIA) disease presents with 4 or fewer affected joints, however after 6 or more months severity might increase with more than 4 joints involved (extended OJIA), or persist with 4 or fewer joints affected (persistent O-JIA). However patients do not show an...
متن کاملPrior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable
BACKGROUND Our intent was to identify differences between the transcriptome of fibroblast-like synoviocytes (FLS) in oligoarticular juvenile idiopathic arthritis (JIA) before extension when compared to persistent subtype of JIA, when the two are clinically indistinguishable. Additionally, we sought to determine if differences between the transcriptomes of FLS from extended-to-be and polyarticul...
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